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Chemical Proteomics
Mass spectrometry-based chemical proteomics technology leverages Chemical Probes to analyze the Ligandability of thousands of proteins in cells or tissues simultaneously. Providing a drug-protein interaction network under physiological conditions. -
DIA-ABPP
abpp
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Automated Chemoproteomic Workstation
ChomiX’s professional biological automation equipment AutoProtChemix can process 96 samples in batches each time, realizing full-process automation of protein extraction, quantification, probe labeling, protein purification, enzyme cleavage and separation. Compared with the existing process dominated by manual operation, this equipment can ensure the accuracy and stability of the experimental process.
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Photoaffinity probes
Photoaffinity Probes Specialized biochemical tools used in molecular biology and drug discovery to study the interactions between a target molecule (such as a protein) and a small molecule or ligand (mainly non-covalent).Widely used in active small molecule target discovery, off-target protein identification and distribution imaging. Many active small molecule compounds, such as metabolites, natural products, and drug molecules, interact dynamically and reversibly with target proteins in... -
Bioorthogonal Chemical Probes
Bioorthogonal chemical probes Specialized tools used in chemical biology to study and manipulate biological processes within living systems without interfering with the native biochemical processes. Usually designed to perform specific chemical reactions that are both highly selective and inert to the plethora of chemical activities occurring in cells. The reactivity of amino acid residues in proteins plays a crucial role in protein function regulation and drug development. Taking cystei... -
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Bioorthogonal Coupling Reaction Kit
It includes KRASG12D protein, small molecule fluorescent probe, and buffer. The probe uses fluorescence polarization technology to simply and quickly test the affinity of compounds to KRASG12D protein in a high-throughput format.
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ChomiX®-ClickKit-Cu/BTTAA C （Click Chemistry Kit）
BTTAA is a new generation of strongly water-soluble ligand, widely used in the CuAAC reaction in solution, matching fluorescein, biotin and other azide-modified reporter groups
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Absolute Protein Quantification Analysis
Absolute Protein Quantification Analysis Absolute quantification analysis is a crucial technique in the field of proteomics, specifically designed to accurately determine the concentration or copy number of proteins or peptides in a sample. The core of this method lies in the precise calibration using known concentrations of the standards (usually isotopically labeled peptides). Absolute quantification analysis is of significant importance for both basic biological research and clinical appli... -
Targeted Proteomics Analysis
Targeted Proteomics Analysis Proteomics research can be divided into targeted and non-targeted proteomics based on whether the study focuses on specific types of proteins. Targeted proteomics is a research method that focuses on specific proteins or protein groups. It selectively detects and quantifies target proteins, providing highly sensitive and specific results, which are used to delve into protein functions and disease mechanisms. Compared to non-targeted proteomics, targeted prote... -
Untargeted Protein Qualitative/Quantitative Analysis
Untargeted Protein Qualitative/Quantitative Analysis In the field of drug development, scientists have been dedicated to exploring innovative therapies for specific diseases. Differential protein analysis has become a key tool for gaining insight into disease molecular mechanisms, identifying effective therapeutic targets, and providing critical clues and scientific evidence for the discovery and development of novel drugs. This technology empowers researchers to systematically detect changes... -
Protein Qualitative and Quantitative Analysis
Protein Qualitative and Quantitative Analysis As a core technology in modern biomedical research, protein qualitative and quantitative analysis, supported by the rapid development of mass spectrometry technology, has achieved precise identification and quantification of proteins. This technology plays a pivotal role in revealing the mysteries of life phenomena, exploring disease mechanisms, and discovering biomarkers. Currently, it is widely used in various fields: Biological Mechanism E...